Further structural studies of 1-indanone derivatives obtained from Onychium japonicum.
نویسندگان
چکیده
منابع مشابه
Novel Fluorinated Indanone, Tetralone and Naphthone Derivatives: Synthesis and Unique Structural Features
Several fluorinated and trifluoromethylated indanone, tetralone and naphthone derivatives have been prepared via Claisen condensations and selective fluorinations in yields ranging from 22–60%. In addition, we report the synthesis of new, selectively fluorinated bindones in yields ranging from 72–92%. Of particular interest is the fluorination and trifluoroacetylation regiochemistry observed in...
متن کاملBeckmann Rearrangements of 1-Indanone Oxime Derivatives Using Aluminum Chloride and Mechanistic Considerations
Hydrocarbostyril, which is a key intermediate in our new synthetic route to 6-nitroquipazine, can be prepared from 1-indanone oxime by Beckmann rearrangement. We have optimized the reaction by using a Lewis acid, aluminum chloride, in the yield of 91% instead of common acids such as polyphosphoric acid, and sulfuric acid used in conventional Beckmann rearrangement (20% in the literature, 10% in...
متن کاملInvestigation of the Molecules Obtained from Marijuana: Computational Study of Spectral, Structural and Docking
There are many chemical molecules whose names are Cannabigerol (CBG), cannabidol (CBD), cannabichromene (CBC), tetrahydrocannabivarin (THCV), cannabigerovarinic acid (CBGV) and cannabidiolic acid (CBDA) derived from Marijuana. Theoretical methods were used to compare the chemical and biological activities of the six major molecules. Molecules were compared with their chemical activities using m...
متن کاملFurther studies of the Enhanced Structural Carborane Effect: tricarbonylruthenium and related derivatives of benzocarborane, dihydrobenzocarborane and biphenylcarborane.
Detailed comparison of the molecular structures of [1,2-μ-(C4H4)-3,3,3-(CO)3-3,1,2-closo-RuC2B9H9] (1) and [1,2-μ-(C4H6)-3,3,3-(CO)3-3,1,2-closo-RuC2B9H9] (2) reveals evidence for an Enhanced Structural Carborane Effect in 1 arising from the involvement of the cage pπ orbitals in the exopolyhedral ring to some degree. A minor co-product in the synthesis of 2 is [η-{1,2-μ-(C4H6)}-3,3-(CO)2-3,1,2...
متن کاملSynthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum.
The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1980
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.28.1311